Human IFI30 protein (Recombinant) (N-His) (STJP004056)

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STJP004056
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IFI30-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IFI30
Gene ID: 10437
Uniprot ID: GILT_HUMAN
Immunogen Region: Met1-Lys250
Immunogen: Homo sapiens (Human)
Function Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation.
Protein Name Gamma-Interferon-Inducible Lysosomal Thiol Reductase
Gamma-Interferon-Inducible Protein Ip-30
Legumaturain
Database Links Reactome: R-HSA-2132295
Reactome: R-HSA-877300
Cellular Localisation Secreted
Lysosome
Alternative Protein Names Gamma-Interferon-Inducible Lysosomal Thiol Reductase protein
Gamma-Interferon-Inducible Protein Ip-30 protein
Legumaturain protein
IFI30 protein
GILT protein
IP30 protein

Information sourced from Uniprot.org

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