Human IDS protein (Recombinant) (N-His) (STJP004346)

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STJP004346
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IDS-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IDS
Gene ID: 3423
Uniprot ID: IDS_HUMAN
Immunogen Region: Arg95-Pro289
Immunogen: Homo sapiens (Human)
Post Translational Modifications Synthesized as a 75-kDa precursor form in the endoplasmic reticulum (ER), and then processed by proteolytic cleavage through various intermediates to yield a 55-kDa mature form, with the release of an 18 kDa polypeptide. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
Function Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate.
Protein Name Iduronate 2-Sulfatase
Alpha-L-Iduronate Sulfate Sulfatase
Idursulfase Cleaved Into - Iduronate 2-Sulfatase 42 Kda Chain - Iduronate 2-Sulfatase 14 Kda Chain
Database Links Reactome: R-HSA-2024096
Reactome: R-HSA-2024101
Reactome: R-HSA-2206296
Cellular Localisation Lysosome
Alternative Protein Names Iduronate 2-Sulfatase protein
Alpha-L-Iduronate Sulfate Sulfatase protein
Idursulfase Cleaved Into - Iduronate 2-Sulfatase 42 Kda Chain - Iduronate 2-Sulfatase 14 Kda Chain protein
IDS protein
SIDS protein

Information sourced from Uniprot.org

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