Tissue Specificity | Liver, kidney, lung, and placenta. |
Post Translational Modifications | Synthesized as a 75-kDa precursor form in the endoplasmic reticulum (ER), and then processed by proteolytic cleavage through various intermediates to yield a 55-kDa mature form, with the release of an 18 kDa polypeptide. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
Function | Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate. |
Protein Name | Iduronate 2-SulfataseAlpha-L-Iduronate Sulfate SulfataseIdursulfase Cleaved Into - Iduronate 2-Sulfatase 42 Kda Chain - Iduronate 2-Sulfatase 14 Kda Chain |
Database Links | Reactome: R-HSA-2024096Reactome: R-HSA-2024101Reactome: R-HSA-2206296 |
Cellular Localisation | Lysosome |
Alternative ELISA Names | Iduronate 2-Sulfatase ELISA kitAlpha-L-Iduronate Sulfate Sulfatase ELISA kitIdursulfase Cleaved Into - Iduronate 2-Sulfatase 42 Kda Chain - Iduronate 2-Sulfatase 14 Kda Chain ELISA kitIDS ELISA kitSIDS ELISA kit |
output | |
Information sourced from Uniprot.org