| Host: | E.coli |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human IDH1 (R132H)-C-8*His protein was developed from e.coli and has a target region of C-8*His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Supplied as a 0.22 Mu m filtered solution in 50mM Tris-HCl, 4% Sucrose, 50% Glycerol, 0.02% Tween 80, pH 8.0. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | IDH1 |
| Gene ID: | 3417 |
| Uniprot ID: | IDHC_HUMAN |
| Immunogen Region: | Met1-Leu414 (R132H) |
| Immunogen: | Homo sapiens (Human) |
| Function | Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways. May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency. |
| Protein Name | Isocitrate Dehydrogenase Nadp CytoplasmicIdhIdh1Cytosolic Nadp-Isocitrate DehydrogenaseIdpcNadp(+-Specific IcdhOxalosuccinate Decarboxylase |
| Database Links | Reactome: R-HSA-2978092Reactome: R-HSA-389542Reactome: R-HSA-6798695Reactome: R-HSA-9033241Reactome: R-HSA-9818025 |
| Cellular Localisation | CytoplasmCytosolPeroxisome |
| Alternative Protein Names | Isocitrate Dehydrogenase Nadp Cytoplasmic proteinIdh proteinIdh1 proteinCytosolic Nadp-Isocitrate Dehydrogenase proteinIdpc proteinNadp(+-Specific Icdh proteinOxalosuccinate Decarboxylase proteinIDH1 proteinPICD protein |
Information sourced from Uniprot.org
