• Human ICAM-2/CD102 protein (Recombinant) (C-hFc&His) (STJP001058)

Human ICAM-2/CD102 protein (Recombinant) (C-hFc&His) (STJP001058)

SKU:
STJP001058

£59.50 - £156.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human ICAM-2/CD102-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Endotoxin: Please contact us for more information.
Immunoreactivity: Measured by the ability of the immobilized protein to support the adhesion of THP-1 cells. When cells are added to ICAM-2 coated plates (12.5 Mu g/mL, 100 Mu L/well) , approximately >40% cells will adhere specifically after 60 minutes at 37 °C.
Gene Symbol: ICAM2
Gene ID: 3384
Uniprot ID: ICAM2_HUMAN
Immunogen: Recombinant Human ICAM-2/CD102 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Lys25-Gln216) of human ICAM-2 (Accession #NP_000864.2) fused with an Fc, 6×His tag at the C-terminus.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Protein Name Intercellular Adhesion Molecule 2
Icam-2
Cd Antigen Cd102
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-5621575
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Microvillus
Co-Localizes With Rdx
Ezr And Msn In Microvilli
Alternative Protein Names Intercellular Adhesion Molecule 2 protein
Icam-2 protein
Cd Antigen Cd102 protein
ICAM2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance