Human HYOU1 protein (Recombinant) (C-10*His) (STJP013616)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HYOU1-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | HYOU1 |
| Gene ID | 10525 |
| Uniprot ID | HYOU1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met695-Leu999 |
Additional Info
| Function | Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. Promotes HSPA5/BiP-mediated ATP nucleotide exchange and thereby activates the unfolded protein response (UPR) pathway in the presence of endoplasmic reticulum stress. May play a role as a molecular chaperone and participate in protein folding. |
| Protein Name | Hypoxia Up-Regulated Protein 1150 Kda Oxygen-Regulated ProteinOrp-150170 Kda Glucose-Regulated ProteinGrp-170Heat Shock Protein Family H Member 4 |
| Database Links | Reactome: R-HSA-3000484Reactome: R-HSA-381038 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Protein Names | Hypoxia Up-Regulated Protein 1 protein150 Kda Oxygen-Regulated Protein proteinOrp-150 protein170 Kda Glucose-Regulated Protein proteinGrp-170 proteinHeat Shock Protein Family H Member 4 proteinHYOU1 proteinGRP170 proteinHSPH4 proteinORP150 protein |
Information sourced from Uniprot.org