Human HTR7 protein (Recombinant) (N-His-SUMO) (STJP007997)

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STJP007997
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HTR7-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HTR7
Gene ID: 3363
Uniprot ID: 5HT7R_HUMAN
Immunogen Region: Met258-Ala325
Immunogen: Homo sapiens (Human)
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity.
Protein Name 5-Hydroxytryptamine Receptor 7
5-Ht-7
5-Ht7
5-Ht-X
Serotonin Receptor 7
Database Links Reactome: R-HSA-390666
Reactome: R-HSA-418555
Reactome: R-HSA-9706019 P34969-2
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names 5-Hydroxytryptamine Receptor 7 protein
5-Ht-7 protein
5-Ht7 protein
5-Ht-X protein
Serotonin Receptor 7 protein
HTR7 protein

Information sourced from Uniprot.org