Tissue Specificity | Expressed in fetal brain. |
Post Translational Modifications | N-glycosylated. |
Function | 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid. |
Protein Name | Heparan-Sulfate 6-O-Sulfotransferase 1Hs6st-1 |
Database Links | Reactome: R-HSA-2022928 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative ELISA Names | Heparan-Sulfate 6-O-Sulfotransferase 1 ELISA kitHs6st-1 ELISA kitHS6ST1 ELISA kitHS6ST ELISA kit |
output | |
Information sourced from Uniprot.org