Tissue Specificity | Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node. |
Post Translational Modifications | |
Function | The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). |
Protein Name | Histamine H4 ReceptorH4rHh4rAxor35G-Protein Coupled Receptor 105Gprv53Pfi-013Sp9144 |
Database Links | Reactome: R-HSA-390650Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | Histamine H4 Receptor ELISA kitH4r ELISA kitHh4r ELISA kitAxor35 ELISA kitG-Protein Coupled Receptor 105 ELISA kitGprv53 ELISA kitPfi-013 ELISA kitSp9144 ELISA kitHRH4 ELISA kitGPCR105 ELISA kit |
output | |
Information sourced from Uniprot.org