Human HRH1 protein (Recombinant) (C-His) (STJP006983)

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STJP006983
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HRH1-C-His protein was developed from e. coli and has a target region of C-His. For use in research applications.
Formulation: 0.01M PBS, pH 7.4.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HRH1
Gene ID: 3269
Uniprot ID: HRH1_HUMAN
Immunogen Region: Lys212-Gln416
Immunogen: Homo sapiens (Human)
Function G-protein-coupled receptor for histamine, a biogenic amine that functions as an immune modulator and a neurotransmitter. Through the H1 receptor, histamine mediates the contraction of smooth muscles and increases capillary permeability due to contraction of terminal venules. Also mediates neurotransmission in the central nervous system and thereby regulates circadian rhythms, emotional and locomotor activities as well as cognitive functions.
Protein Name Histamine H1 Receptor
H1-R
H1r
Hh1r
Database Links Reactome: R-HSA-390650
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Histamine H1 Receptor protein
H1-R protein
H1r protein
Hh1r protein
HRH1 protein

Information sourced from Uniprot.org