| Short Description : | Recombinant-Human HRH1-C-His protein was developed from e.coli for the region C-His. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | 0.01M PBS, pH 7.4. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | HRH1 |
| Gene ID: | 3269 |
| Uniprot ID: | HRH1_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Lys212-Gln416 |
| Function | G-protein-coupled receptor for histamine, a biogenic amine that functions as an immune modulator and a neurotransmitter. Through the H1 receptor, histamine mediates the contraction of smooth muscles and increases capillary permeability due to contraction of terminal venules. Also mediates neurotransmission in the central nervous system and thereby regulates circadian rhythms, emotional and locomotor activities as well as cognitive functions. |
| Protein Name | Histamine H1 ReceptorH1-RH1rHh1r |
| Database Links | Reactome: R-HSA-390650Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Histamine H1 Receptor proteinH1-R proteinH1r proteinHh1r proteinHRH1 protein |
Information sourced from Uniprot.org