Tissue Specificity | |
Post Translational Modifications | Regulated by cell cycle-dependent phosphorylation which alters its DNA binding affinity. Phosphorylated by NEK2. |
Function | Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation. Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner. |
Protein Name | High Mobility Group Protein Hmgi-CHigh Mobility Group At-Hook Protein 2 |
Database Links | Reactome: R-HSA-2559584 |
Cellular Localisation | Nucleus |
Alternative ELISA Names | High Mobility Group Protein Hmgi-C ELISA kitHigh Mobility Group At-Hook Protein 2 ELISA kitHMGA2 ELISA kitHMGIC ELISA kit |
output | |
Information sourced from Uniprot.org