Human HMG20A protein (Recombinant) (N-His) (STJP007847)

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STJP007847
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HMG20A-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HMG20A
Gene ID: 10363
Uniprot ID: HM20A_HUMAN
Immunogen Region: Ile220-Arg347
Immunogen: Homo sapiens (Human)
Function Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.
Protein Name High Mobility Group Protein 20a
Hmg Box-Containing Protein 20a
Hmg Domain-Containing Protein 1
Hmg Domain-Containing Protein Hmgx1
Cellular Localisation Nucleus
Alternative Protein Names High Mobility Group Protein 20a protein
Hmg Box-Containing Protein 20a protein
Hmg Domain-Containing Protein 1 protein
Hmg Domain-Containing Protein Hmgx1 protein
HMG20A protein
HMGX1 protein
HMGXB1 protein

Information sourced from Uniprot.org