Function | Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4. |
Protein Name | High Mobility Group Protein 20aHmg Box-Containing Protein 20aHmg Domain-Containing Protein 1Hmg Domain-Containing Protein Hmgx1 |
Cellular Localisation | Nucleus |
Alternative Protein Names | High Mobility Group Protein 20a proteinHmg Box-Containing Protein 20a proteinHmg Domain-Containing Protein 1 proteinHmg Domain-Containing Protein Hmgx1 proteinHMG20A proteinHMGX1 proteinHMGXB1 protein |
Information sourced from Uniprot.org