Human HERC4 protein (Recombinant) (N-His-SUMO) (STJP010034)

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STJP010034
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HERC4-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HERC4
Gene ID: 26091
Uniprot ID: HERC4_HUMAN
Immunogen Region: Met607-Lys787
Immunogen: Homo sapiens (Human)
Function Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.
Protein Name Probable E3 Ubiquitin-Protein Ligase Herc4
Hect Domain And Rcc1-Like Domain-Containing Protein 4
Hect-Type E3 Ubiquitin Transferase Herc4
Database Links Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Cytosol
Shows A Punctate Cytoplasmic Distribution
Alternative Protein Names Probable E3 Ubiquitin-Protein Ligase Herc4 protein
Hect Domain And Rcc1-Like Domain-Containing Protein 4 protein
Hect-Type E3 Ubiquitin Transferase Herc4 protein
HERC4 protein
KIAA1593 protein

Information sourced from Uniprot.org

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