Human HEPH protein (Recombinant) (N-His) (STJP005932)

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STJP005932
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HEPH-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HEPH
Gene ID: 9843
Uniprot ID: HEPH_HUMAN
Immunogen Region: Ala24-Cys366
Immunogen: Homo sapiens (Human)
Function Plasma membrane ferroxidase that mediates the extracellular conversion of ferrous/Fe(2+) iron into its ferric/Fe(3+) form. Couples ferroportin which specifically exports ferrous/Fe(2+) iron from cells to transferrin that only binds and shuttles extracellular ferric/Fe(3+) iron throughout the body. By helping iron transfer from cells to blood mainly contributes to dietary iron absorption by the intestinal epithelium and more generally regulates iron levels in the body.
Protein Name Hephaestin
Hp
Database Links Reactome: R-HSA-425410
Reactome: R-HSA-5655799
Reactome: R-HSA-917937
Cellular Localisation Basolateral Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Hephaestin protein
Hp protein
HEPH protein
KIAA0698 protein
UNQ2562 protein
PRO6242 protein

Information sourced from Uniprot.org