Name: Human HEPC/Hepcidin protein (Recombinant) (N-GST & C-His) (STJP011503)
SKU: STJP011503
Availability: InStock

Human HEPC/Hepcidin protein (Recombinant) (N-GST & C-His) (STJP011503)

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STJP011503

€410.63 - €1,796.88

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human HEPC/Hepcidin-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes. Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa.
Protein Name	Hepcidin Liver-Expressed Antimicrobial Peptide 1 Leap-1 Putative Liver Tumor Regressor Pltr Cleaved Into - Hepcidin-25 Hepc25 - Hepcidin-20 Hepc20
Cellular Localisation	Secreted
Alternative Protein Names	Hepcidin protein Liver-Expressed Antimicrobial Peptide 1 protein Leap-1 protein Putative Liver Tumor Regressor protein Pltr Cleaved Into - Hepcidin-25 protein Hepc25 - Hepcidin-20 protein Hepc20 protein HAMP protein HEPC protein LEAP1 protein UNQ487 protein PRO1003 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP011131	Mouse HAMP/Hepcidin protein (Recombinant) (N-GST & C-His) (STJP011131)	E. coli
STJP011289	Human SOX9, N-GST & C-His protein (Recombinant) (N-GST & C-His) (STJP011289)	E. coli
STJP009619	Human WAS protein (Recombinant) (N-GST & C-His) (STJP009619)	E. coli
STJP008899	Human SEMG1 protein (Recombinant) (N-GST & C-His) (STJP008899)	E. coli
STJP008840	Human GPR37 protein (Recombinant) (N-GST & C-His) (STJP008840)	E. coli

Human HEPC/Hepcidin protein (Recombinant) (N-GST & C-His) (STJP011503)

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