| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human HCLS1-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | Please contact us for further information. |
| Gene Symbol: | HCLS1 |
| Gene ID: | 3059 |
| Uniprot ID: | HCLS1_HUMAN |
| Immunogen Region: | Gly430-Glu486 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Phosphorylated by FES. Phosphorylated by LYN, FYN and FGR after cross-linking of surface IgM on B-cells. Phosphorylation by LYN, FYN and FGR requires prior phosphorylation by SYK or FES. |
| Function | Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. |
| Protein Name | Hematopoietic Lineage Cell-Specific ProteinHematopoietic Cell-Specific Lyn Substrate 1Lckbp1P75 |
| Database Links | |
| Cellular Localisation | MembranePeripheral Membrane ProteinCytoplasmMitochondrion |
| Alternative Protein Names | Hematopoietic Lineage Cell-Specific Protein proteinHematopoietic Cell-Specific Lyn Substrate 1 proteinLckbp1 proteinP75 proteinHCLS1 proteinHS1 protein |
Information sourced from Uniprot.org