| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human HBP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | HBP1 |
| Gene ID: | 26959 |
| Uniprot ID: | HBP1_HUMAN |
| Immunogen Region: | Arg220-Ser311 |
| Immunogen: | Homo sapiens (Human) |
| Function | Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. |
| Protein Name | Hmg Box-Containing Protein 1Hmg Box Transcription Factor 1High Mobility Group Box Transcription Factor 1 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Hmg Box-Containing Protein 1 proteinHmg Box Transcription Factor 1 proteinHigh Mobility Group Box Transcription Factor 1 proteinHBP1 protein |
Information sourced from Uniprot.org