Tissue Specificity | Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine. |
Post Translational Modifications | |
Function | Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate. |
Protein Name | Hyaluronan Synthase 1Hyaluronate Synthase 1Hyaluronic Acid Synthase 1Ha Synthase 1Huhas1 |
Database Links | Reactome: R-HSA-2142850 |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | Hyaluronan Synthase 1 ELISA kitHyaluronate Synthase 1 ELISA kitHyaluronic Acid Synthase 1 ELISA kitHa Synthase 1 ELISA kitHuhas1 ELISA kitHAS1 ELISA kitHAS ELISA kit |
output | |
Information sourced from Uniprot.org