| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 5.9pg/mL |
| Detection Limit: | 15.6-1000pg/mL |
| Short Description : | This GZMM Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | GZMM |
| Gene ID: | 3004 |
| Uniprot ID: | GRAM_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Highly and constitutively expressed in activated natural killer (NK) cells. |
| Post Translational Modifications | |
| Function | Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells. |
| Protein Name | Granzyme MMet-1 Serine ProteaseHu-Met-1Met-AseNatural Killer Cell Granular Protease |
| Database Links | Reactome: R-HSA-173736 |
| Cellular Localisation | SecretedCytoplasmic GranuleGranules Of Large Granular Lymphocytes |
| Alternative ELISA Names | Granzyme M ELISA kitMet-1 Serine Protease ELISA kitHu-Met-1 ELISA kitMet-Ase ELISA kitNatural Killer Cell Granular Protease ELISA kitGZMM ELISA kitMET1 ELISA kit |
| output |
Information sourced from Uniprot.org
