Tissue Specificity | Constitutively expressed in NK cells. |
Post Translational Modifications | |
Function | Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication. |
Protein Name | Granzyme HCcp-XCathepsin G-Like 2Ctsgl2Cytotoxic T-Lymphocyte ProteinaseCytotoxic Serine Protease CCsp-C |
Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-381426 |
Cellular Localisation | Cytolytic Granule |
Alternative ELISA Names | Granzyme H ELISA kitCcp-X ELISA kitCathepsin G-Like 2 ELISA kitCtsgl2 ELISA kitCytotoxic T-Lymphocyte Proteinase ELISA kitCytotoxic Serine Protease C ELISA kitCsp-C ELISA kitGZMH ELISA kitCGL2 ELISA kitCTSGL2 ELISA kit |
output | |
Information sourced from Uniprot.org