| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human GPR17-N-His-KSI protein was developed from e. coli and has a target region of N-His-KSI. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | GPR17 |
| Gene ID: | 2840 |
| Uniprot ID: | GPR17_HUMAN |
| Immunogen Region: | [Ser2-Ser64] & [Ala329-Leu367] |
| Immunogen: | Homo sapiens (Human) |
| Function | Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. |
| Protein Name | Uracil Nucleotide/Cysteinyl Leukotriene ReceptorUdp/Cyslt ReceptorG-Protein Coupled Receptor 17P2y-Like ReceptorR12 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476Reactome: R-HSA-417957Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Uracil Nucleotide/Cysteinyl Leukotriene Receptor proteinUdp/Cyslt Receptor proteinG-Protein Coupled Receptor 17 proteinP2y-Like Receptor proteinR12 proteinGPR17 protein |
Information sourced from Uniprot.org