| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human GPBAR1-N-His-KSI protein was developed from e. coli and has a target region of N-His-KSI. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | GPBAR1 |
| Gene ID: | 151306 |
| Uniprot ID: | GPBAR_HUMAN |
| Immunogen Region: | [Thr2-Gly19] & [Pro72-Cys85] & [Asn147-Tyr165] & [Ala250-Thr261] & [Gly283-Asn330] |
| Immunogen: | Homo sapiens (Human) |
| Function | Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. |
| Protein Name | G-Protein Coupled Bile Acid Receptor 1G-Protein Coupled Receptor Gpcr19Hgpcr19Membrane-Type Receptor For Bile AcidsM-BarHbg37Bg37 |
| Database Links | Reactome: R-HSA-373076Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | G-Protein Coupled Bile Acid Receptor 1 proteinG-Protein Coupled Receptor Gpcr19 proteinHgpcr19 proteinMembrane-Type Receptor For Bile Acids proteinM-Bar proteinHbg37 proteinBg37 proteinGPBAR1 proteinTGR5 protein |
Information sourced from Uniprot.org