Human GOLPH3 protein (Recombinant) (N-His) (STJP007514)

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STJP007514
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GOLPH3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GOLPH3
Gene ID: 64083
Uniprot ID: GOLP3_HUMAN
Immunogen Region: Thr58-Lys298
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated.
Function Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis.
Protein Name Golgi Phosphoprotein 3
Coat Protein Gpp34
Mitochondrial Dna Absence Factor
Midas
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Trans-Golgi Network Membrane
Mitochondrion Intermembrane Space
Cell Membrane
Endosome
Phosphatidylinositol 4-Phosphate-Binding And Oligomerization Participate In The Recruitment Onto Golgi Membranes
Alternative Protein Names Golgi Phosphoprotein 3 protein
Coat Protein Gpp34 protein
Mitochondrial Dna Absence Factor protein
Midas protein
GOLPH3 protein
GPP34 protein

Information sourced from Uniprot.org