| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human GNMT-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | GNMT |
| Gene ID: | 27232 |
| Uniprot ID: | GNMT_HUMAN |
| Immunogen Region: | Met1-Asp295 |
| Immunogen: | Homo sapiens (Human) |
| Function | Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate. Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine. |
| Protein Name | Glycine N-Methyltransferase |
| Database Links | Reactome: R-HSA-2408508Reactome: R-HSA-389661 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Glycine N-Methyltransferase proteinGNMT protein |
Information sourced from Uniprot.org