Human GMNN protein (Recombinant) (N-GST) (STJP003360)

SKU:
STJP003360
€410.63 - €1,796.88
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GMNN-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GMNN
Gene ID: 51053
Uniprot ID: GEMI_HUMAN
Immunogen Region: Met1-Ile209
Immunogen: Homo sapiens (Human)
Function Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control.
Protein Name Geminin
Database Links Reactome: R-HSA-68867
Reactome: R-HSA-68962
Reactome: R-HSA-69052
Cellular Localisation Cytoplasm
Nucleus
Mainly Cytoplasmic But Can Be Relocalized To The Nucleus
Alternative Protein Names Geminin protein
GMNN protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP007291 Human MXI1 protein (Recombinant) (N-GST) (STJP007291) E. coli
STJP010311 Human TNFAIP3 protein (Recombinant) (N-GST) (STJP010311) E. coli
STJP010340 Human MUC5B protein (Recombinant) (N-GST) (STJP010340) E. coli
STJP010012 Human OCEL1 protein (Recombinant) (N-GST) (STJP010012) E. coli
STJP010015 Human DOCK5 protein (Recombinant) (N-GST) (STJP010015) E. coli
!