Human GLUD1 protein (Recombinant) (N-His) (STJP003465)

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STJP003465
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GLUD1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GLUD1
Gene ID: 2746
Uniprot ID: DHE3_HUMAN
Immunogen Region: Asp334-Thr556
Immunogen: Homo sapiens (Human)
Function Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. Plays a role in insulin homeostasis. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate.
Protein Name Glutamate Dehydrogenase 1 - Mitochondrial
Gdh 1
Database Links Reactome: R-HSA-2151201
Reactome: R-HSA-8964539
Reactome: R-HSA-9837999
Cellular Localisation Mitochondrion
Endoplasmic Reticulum
Mostly Translocates Into The Mitochondria
Only A Small Amount Of The Protein Localizes To The Endoplasmic Reticulum
Alternative Protein Names Glutamate Dehydrogenase 1 - Mitochondrial protein
Gdh 1 protein
GLUD1 protein
GLUD protein

Information sourced from Uniprot.org