Human GK protein (Recombinant) (N-His) (STJP008193)

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STJP008193
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GK-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GK
Gene ID: 2710
Uniprot ID: GLPK_HUMAN
Immunogen Region: Met1-Pro559
Immunogen: Homo sapiens (Human)
Function Kinase that plays a key role in glycerol metabolism, catalyzing its phosphorylation to produce sn-glycerol 3-phosphate. Sn-glycerol 3-phosphate is a crucial intermediate in various metabolic pathways, such as the synthesis of glycerolipids and triglycerides, glycogenesis, glycolysis and gluconeogenesis.
Protein Name Glycerol Kinase
Glycerokinase
Atp -Glycerol 3-Phosphotransferase
Database Links Reactome: R-HSA-75109
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Membrane Protein
Nucleus
Cytoplasm
Cytosol
Glycerol Kinase Activity Is More Cytosolic In Some Tissues
It Probably Represents The Expression Of Isoforms Lacking A Transmembrane Domain
Isoform 3: Mitochondrion Outer Membrane
In Sperm And Fetal Tissues
The Majority Of The Activity Is Associated With Mitochondria
Isoform 4: Cytoplasm
In Adult Tissues
Such As Liver The Glycerol Kinase Activity Is More Cytosolic
It Probably Represents The Expression Of This Isoform Which Lacks A Transmembrane Domain
Alternative Protein Names Glycerol Kinase protein
Glycerokinase protein
Atp -Glycerol 3-Phosphotransferase protein
GK protein

Information sourced from Uniprot.org

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