| Short Description : | Recombinant-Active-Human GFRA1-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Immobilised human GDNF at 1 Mu g/mL (100 Mu L/well) can bind human GFRA1 with a linear range of 2-332 ng/mL. |
| Gene Symbol: | GFRA1 |
| Gene ID: | 2674 |
| Uniprot ID: | GFRA1_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ala19-Ser429 |
| Protein Name | Gdnf Family Receptor Alpha-1Gdnf Receptor Alpha-1Gdnfr-Alpha-1Gfr-Alpha-1Ret Ligand 1Tgf-Beta-Related Neurotrophic Factor Receptor 1 |
| Database Links | Reactome: R-HSA-419037Reactome: R-HSA-5673001Reactome: R-HSA-8853659Reactome: R-HSA-9830674 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorGolgi ApparatusTrans-Golgi NetworkEndosomeMultivesicular BodyLocalizes Mainly To The Plasma MembraneIn The Presence Of Sorl1Shifts To Vesicular StructuresIncluding Trans-Golgi NetworkEndosomes And Multivesicular Bodies |
| Alternative Protein Names | Gdnf Family Receptor Alpha-1 proteinGdnf Receptor Alpha-1 proteinGdnfr-Alpha-1 proteinGfr-Alpha-1 proteinRet Ligand 1 proteinTgf-Beta-Related Neurotrophic Factor Receptor 1 proteinGFRA1 proteinGDNFRA proteinRETL1 proteinTRNR1 protein |
Information sourced from Uniprot.org
