Human GDF2 protein (Recombinant) (N-His) (STJP006178)

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STJP006178
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GDF2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GDF2
Gene ID: 2658
Uniprot ID: GDF2_HUMAN
Immunogen Region: Ser320-Arg429
Immunogen: Homo sapiens (Human)
Post Translational Modifications A reversible disulfide bond can be formed between the two subunits in the homodimer.this has no effect on GDF2 activity.
Function Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.
Protein Name Growth/Differentiation Factor 2
Gdf-2
Bone Morphogenetic Protein 9
Bmp-9
Database Links Reactome: R-HSA-201451
Cellular Localisation Secreted
Alternative Protein Names Growth/Differentiation Factor 2 protein
Gdf-2 protein
Bone Morphogenetic Protein 9 protein
Bmp-9 protein
GDF2 protein
BMP9 protein

Information sourced from Uniprot.org