Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human GDF2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | GDF2 |
Gene ID: | 2658 |
Uniprot ID: | GDF2_HUMAN |
Immunogen Region: | Ser320-Arg429 |
Immunogen: | Homo sapiens (Human) |
Post Translational Modifications | A reversible disulfide bond can be formed between the two subunits in the homodimer.this has no effect on GDF2 activity. |
Function | Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. |
Protein Name | Growth/Differentiation Factor 2Gdf-2Bone Morphogenetic Protein 9Bmp-9 |
Database Links | Reactome: R-HSA-201451 |
Cellular Localisation | Secreted |
Alternative Protein Names | Growth/Differentiation Factor 2 proteinGdf-2 proteinBone Morphogenetic Protein 9 proteinBmp-9 proteinGDF2 proteinBMP9 protein |
Information sourced from Uniprot.org