Human GCNT3 protein (Recombinant) (N-His) (STJP010783)

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STJP010783
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GCNT3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GCNT3
Gene ID: 9245
Uniprot ID: GCNT3_HUMAN
Immunogen Region: Leu27-Leu438
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.
Function Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
Protein Name Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3
C2gnt-Mucin Type
C2gnt-M
Hc2gnt-M
Core 2/Core 4 Beta-1 -6-N-Acetylglucosaminyltransferase
C2/4gnt
Database Links Reactome: R-HSA-913709
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 protein
C2gnt-Mucin Type protein
C2gnt-M protein
Hc2gnt-M protein
Core 2/Core 4 Beta-1 -6-N-Acetylglucosaminyltransferase protein
C2/4gnt protein
GCNT3 protein

Information sourced from Uniprot.org