Human GALNT2 protein (Recombinant-Active) (N-His) (STJP012084)

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STJP012084-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human GALNT2-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: GALNT2
Gene ID: 2590
Uniprot ID: GALT2_HUMAN
Immunogen Region: Lys52-Gln571
Immunogen: Homo sapiens (Human)
Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. Involved in O-linked glycosylation of APOC-III, ANGPTL3 and PLTP. It participates in the regulation of HDL-C metabolism.
Protein Name Polypeptide N-Acetylgalactosaminyltransferase 2
Polypeptide Galnac Transferase 2
Galnac-T2
Pp-Gantase 2
Protein-Udp Acetylgalactosaminyltransferase 2
Udp-Galnac -Polypeptide N-Acetylgalactosaminyltransferase 2 Cleaved Into - Polypeptide N-Acetylgalactosaminyltransferase 2 Soluble Form
Database Links Reactome: R-HSA-6811436
Reactome: R-HSA-913709
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Resides Preferentially In The Trans And Medial Parts Of The Golgi Stack
A Secreted Form Also Exists
Alternative Protein Names Polypeptide N-Acetylgalactosaminyltransferase 2 protein
Polypeptide Galnac Transferase 2 protein
Galnac-T2 protein
Pp-Gantase 2 protein
Protein-Udp Acetylgalactosaminyltransferase 2 protein
Udp-Galnac -Polypeptide N-Acetylgalactosaminyltransferase 2 Cleaved Into - Polypeptide N-Acetylgalactosaminyltransferase 2 Soluble Form protein
GALNT2 protein

Information sourced from Uniprot.org

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