Human GAD1/GAD67 protein (Recombinant) (His-Tag) (STJP018739)

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STJP018739
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Covered by St John's Laboratory Guarantee

Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GAD1/GAD67-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.4M urea
Concentration: 0.5 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: GAD1
Gene ID: 2571
Uniprot ID: DCE1_HUMAN
Immunogen Region: 1-224aa
Accession Number: NP_038473.2
Immunogen: Human
Immunogen Sequence: MASSTPS SSATSSNAGA DPNTTNLRPT TYDTWCGVAH GCTRKLGLKI CGFLQRTNSL EEKSRLVSAF KERQSSKNLL SCENSDRDAR FRRTETDFSN LFARDLLPAK NGEEQTVQFL LEVVDILLNY VRKTFDRSTK VLDFHHPHQL LEGMEGFNLE LSDHPESLEQ ILVDCRDTLK YGVRTGHPRF FNQLSTGLDI IGLAGE
Tissue Specificity Isoform 1: Expressed in brain. Isoform 3: Expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain.
Function Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor. Isoform 3: Enzymatically inactive as glutamate decarboxylase.
Protein Name Glutamate Decarboxylase 1
67 Kda Glutamic Acid Decarboxylase
Gad-67
Glutamate Decarboxylase 67 Kda Isoform
Database Links Reactome: R-HSA-888568
Reactome: R-HSA-888590
Reactome: R-HSA-9022927
Cellular Localisation
Alternative Protein Names Glutamate Decarboxylase 1 protein
67 Kda Glutamic Acid Decarboxylase protein
Gad-67 protein
Glutamate Decarboxylase 67 Kda Isoform protein
GAD1 protein
GAD protein
GAD67 protein

Information sourced from Uniprot.org

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