| Short Description : | Recombinant-Active-Human GAA/Aglucosidase alfa-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to release glucose from starch. The specific activity is >7, 500 pmol/min/Mu g, as measured under the described conditions. |
| Gene Symbol: | GAA |
| Gene ID: | 2548 |
| Uniprot ID: | LYAG_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ala70-Cys952 |
| Function | Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. |
| Protein Name | Lysosomal Alpha-GlucosidaseAcid MaltaseAglucosidase Alfa Cleaved Into - 76 Kda Lysosomal Alpha-Glucosidase - 70 Kda Lysosomal Alpha-Glucosidase |
| Database Links | Reactome: R-HSA-5357609Reactome: R-HSA-6798695Reactome: R-HSA-70221 |
| Cellular Localisation | LysosomeLysosome Membrane |
| Alternative Protein Names | Lysosomal Alpha-Glucosidase proteinAcid Maltase proteinAglucosidase Alfa Cleaved Into - 76 Kda Lysosomal Alpha-Glucosidase - 70 Kda Lysosomal Alpha-Glucosidase proteinGAA protein |
Information sourced from Uniprot.org