Human FZD5 protein (Recombinant) (C-His) (STJP012665)

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STJP012665-100
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Host: Mammalian Cells
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FZD5-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: < 1 EU/µg as determined by LAL test.
Gene Symbol: FZD5
Gene ID: 7855
Uniprot ID: FZD5_HUMAN
Immunogen Region: Ala27-Pro167
Immunogen: Homo sapiens (Human)
Function Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling. In neurons, activation by WNT7A promotes formation of synapses. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable). Plays a role in yolk sac angiogenesis and in placental vascularization. Plays a role in ocular development.
Protein Name Frizzled-5
Fz-5
Hfz5
Fze5
Database Links Reactome: R-HSA-373080
Reactome: R-HSA-4086398
Reactome: R-HSA-4608870
Reactome: R-HSA-4641262
Reactome: R-HSA-4641263
Reactome: R-HSA-5140745
Reactome: R-HSA-5340588
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Synapse
Perikaryon
Cell Projection
Dendrite
Axon
Localized At The Plasma Membrane And Also Found At The Golgi Apparatus
Alternative Protein Names Frizzled-5 protein
Fz-5 protein
Hfz5 protein
Fze5 protein
FZD5 protein
C2orf31 protein

Information sourced from Uniprot.org