| Host: | Mammalian Cells |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human FSTL1-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. When recombinant human FSTL1 is coated at 2 Mu g/mL (100 Mu L/well) , the concentration of recombinant human BMP-4 that produces 50% of the optimal binding response is found to be approximately 1 |
| Gene Symbol: | FSTL1 |
| Gene ID: | 11167 |
| Uniprot ID: | FSTL1_HUMAN |
| Immunogen Region: | Glu21-Ile308 |
| Immunogen: | Homo sapiens (Human) |
| Function | Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors. |
| Protein Name | Follistatin-Related Protein 1Follistatin-Like Protein 1 |
| Database Links | Reactome: R-HSA-201451Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Follistatin-Related Protein 1 proteinFollistatin-Like Protein 1 proteinFSTL1 proteinFRP protein |
Information sourced from Uniprot.org