Human FSHR protein (Recombinant) (N-His) (STJP007373)

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STJP007373
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FSHR-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FSHR
Gene ID: 2492
Uniprot ID: FSHR_HUMAN
Immunogen Region: Ser16-Lys349
Immunogen: Homo sapiens (Human)
Post Translational Modifications Sulfated. N-glycosylated.indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone.
Function G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
Protein Name Follicle-Stimulating Hormone Receptor
Fsh-R
Follitropin Receptor
Database Links Reactome: R-HSA-375281
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Follicle-Stimulating Hormone Receptor protein
Fsh-R protein
Follitropin Receptor protein
FSHR protein
LGR1 protein

Information sourced from Uniprot.org