Human FN3K protein (Recombinant) (N-His) (STJP005991)

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STJP005991
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FN3K-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FN3K
Gene ID: 64122
Uniprot ID: FN3K_HUMAN
Immunogen Region: Met1-Lys309
Immunogen: Homo sapiens (Human)
Function Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Involved in intracellular deglycation in erythrocytes. Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function. Also able to phosphorylate psicosamines and ribulosamines.
Protein Name Fructosamine-3-Kinase
Protein-Psicosamine 3-Kinase Fn3k
Protein-Ribulosamine 3-Kinase Fn3k
Database Links Reactome: R-HSA-163841
Alternative Protein Names Fructosamine-3-Kinase protein
Protein-Psicosamine 3-Kinase Fn3k protein
Protein-Ribulosamine 3-Kinase Fn3k protein
FN3K protein

Information sourced from Uniprot.org

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