Human FLT3 Ligand protein (Recombinant) (STJP000239)

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STJP000239

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Host: CHO cells
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human FLT3 Ligand-protein was developed from cho cells. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.2 Mu m filtered PBS solution pH7.0.
Dilution Range: Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction: Can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA
Immunoreactivity: The ED (50) was determined by the dose-dependent stimulation of the proliferation of Human AML5 cells was found to be in the range of.0 ng/ml. NA
Gene Symbol: FLT3LG
Gene ID: 2323
Uniprot ID: FLT3L_HUMAN
Immunogen Region: Mature chain
Immunogen: Optimized DNA sequence encoding Human FLT-3 Ligandmature chain was expressed in CHO cells NA
Immunogen Sequence: MTVLAPAWSP TTYLLLLLLL SSGLSGTQDC SFQHSPISSD FAVKIRELSD YLLQDYPVTV ASNLQDEELC GGLWRLVLAQ RWMERLKTVA GSKMQGLLER VNTEIHFVTK CAFQPPPSCL RFVQTNISRL LQETSEQLVA LKPWITRQNF SRCLELQCQP DSSTLPPPWS PRPLEATAPT A PQPPLLLLL LLPVGLLLLA AAWCLHWQRT RRRTPRPGEQ VPPVPSP
Function Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Protein Name Fms-Related Tyrosine Kinase 3 Ligand
Flt3 Ligand
Flt3l
Sl Cytokine
Database Links Reactome: R-HSA-109704
Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-5673001
Reactome: R-HSA-6811558
Reactome: R-HSA-9607240
Reactome: R-HSA-9645135
Reactome: R-HSA-9706369
Reactome: R-HSA-9706374
Reactome: R-HSA-9706377
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Protein Names Fms-Related Tyrosine Kinase 3 Ligand protein
Flt3 Ligand protein
Flt3l protein
Sl Cytokine protein
FLT3LG protein

Information sourced from Uniprot.org

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