Human FLNC protein (Recombinant) (N-His) (STJP005395)

SKU:
STJP005395
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FLNC-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FLNC
Gene ID: 2318
Uniprot ID: FLNC_HUMAN
Immunogen Region: Glu17-Lys259
Immunogen: Homo sapiens (Human)
Post Translational Modifications Ubiquitinated by FBXL22, leading to proteasomal degradation.
Function Muscle-specific filamin, which plays a central role in sarcomere assembly and organization. Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events.
Protein Name Filamin-C
Fln-C
Flnc
Abp-280-Like Protein
Abp-L
Actin-Binding-Like Protein
Filamin-2
Gamma-Filamin
Database Links Reactome: R-HSA-446353
Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
Cytoskeleton
Myofibril
Sarcomere
Z Line
A Small Amount Localizes At Membranes
In Striated Muscle Cells
It Predominantly Localizes In Myofibrillar Z Lines
While A Minor Fraction Localizes With Subsarcolemme
Targeting To Developing And Mature Z Lines Is Mediated By The Intradomain Insert
Alternative Protein Names Filamin-C protein
Fln-C protein
Flnc protein
Abp-280-Like Protein protein
Abp-L protein
Actin-Binding-Like Protein protein
Filamin-2 protein
Gamma-Filamin protein
FLNC protein
ABPL protein
FLN2 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP011684 Human OTUD4 protein (Recombinant) (N-His) (STJP011684) E. coli
STJP011639 Human ERFE protein (Recombinant) (N-His) (STJP011639) E. coli
STJP011680 Human TMED3 protein (Recombinant) (N-His) (STJP011680) E. coli

Related Products

!