| Host: | E.coli |
| Applications: | SDS-PAGE/Enzyme Activity |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human FKBP25/FKBP3-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Specific activity is > 900nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmol of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin. |
| Gene Symbol: | FKBP3 |
| Gene ID: | 2287 |
| Uniprot ID: | FKBP3_HUMAN |
| Immunogen Region: | 1-224aa |
| Accession Number: | NP_002004 |
| Immunogen: | Human |
| Immunogen Sequence: | MAAAVPQRAW TVEQLRSEQL PKKDIIKFLQ EHGSDSFLAE HKLLGNIKNV AKTANKDHLV TAYNHLFETK RFKGTESISK VSEQVKNVKL NEDKPKETKS EETLDEGPPK YTKSVLKKGD KTNFPKKGDV VHCWYTGTLQ DGTVFDTNIQ TSAKKKKNAK PLSFKVGVGK VIRGWDEALL TMSKGEKARL EIEPEWAYGK KGQPDAKIPP NAKLTFEVEL VDID |
| Function | FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase Fkbp3Ppiase Fkbp325 Kda Fk506-Binding Protein25 Kda FkbpFkbp-25Fk506-Binding Protein 3Fkbp-3Immunophilin Fkbp25Rapamycin-Selective 25 Kda ImmunophilinRotamase |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Peptidyl-Prolyl Cis-Trans Isomerase Fkbp3 proteinPpiase Fkbp3 protein25 Kda Fk506-Binding Protein protein25 Kda Fkbp proteinFkbp-25 proteinFk506-Binding Protein 3 proteinFkbp-3 proteinImmunophilin Fkbp25 proteinRapamycin-Selective 25 Kda Immunophilin proteinRotamase proteinFKBP3 proteinFKBP25 protein |
Information sourced from Uniprot.org