| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human FGF19-N-His tag protein was developed from e. coli and has a target region of N-His tag. For use in research applications. |
| Formulation: | 0.01M PBS, pH 7.4. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | FGF19 |
| Gene ID: | 9965 |
| Uniprot ID: | FGF19_HUMAN |
| Immunogen Region: | Phe27-Lys216 |
| Immunogen: | Homo sapiens (Human) |
| Function | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. |
| Protein Name | Fibroblast Growth Factor 19Fgf-19 |
| Database Links | Reactome: R-HSA-109704Reactome: R-HSA-1257604Reactome: R-HSA-1307965Reactome: R-HSA-190322Reactome: R-HSA-2219530Reactome: R-HSA-5654228Reactome: R-HSA-5654712Reactome: R-HSA-5654719Reactome: R-HSA-5654720Reactome: R-HSA-5654733Reactome: R-HSA-5673001Reactome: R-HSA-6811558 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Fibroblast Growth Factor 19 proteinFgf-19 proteinFGF19 proteinUNQ334 proteinPRO533 protein |
Information sourced from Uniprot.org
