| Post Translational Modifications | May be phosphorylated. |
| Function | Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons. |
| Protein Name | Fibroblast Growth Factor 13Fgf-13Fibroblast Growth Factor Homologous Factor 2Fhf-2 |
| Database Links | Reactome: R-HSA-5576892 |
| Cellular Localisation | Isoform 1: NucleusIsoform 2: CytoplasmNucleusIsoform 3: CytoplasmIsoform 4: CytoplasmIsoform 5: CytoplasmCell ProjectionFilopodiumGrowth ConeDendriteCell MembraneSarcolemmaCytoplasmNot SecretedLocalizes To The Lateral Membrane And Intercalated Disks Of Myocytes |
| Alternative Protein Names | Fibroblast Growth Factor 13 proteinFgf-13 proteinFibroblast Growth Factor Homologous Factor 2 proteinFhf-2 proteinFGF13 proteinFHF2 protein |
Information sourced from Uniprot.org
