Human FGF13 protein (Recombinant) (N-His) (STJP005803)

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STJP005803
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Short Description :Recombinant-Human FGF13-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:FGF13
Gene ID:2258
Uniprot ID:FGF13_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Gly108-Arg227
Post Translational Modifications May be phosphorylated.
Function Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons.
Protein Name Fibroblast Growth Factor 13
Fgf-13
Fibroblast Growth Factor Homologous Factor 2
Fhf-2
Database Links Reactome: R-HSA-5576892
Cellular Localisation Isoform 1: Nucleus
Isoform 2: Cytoplasm
Nucleus
Isoform 3: Cytoplasm
Isoform 4: Cytoplasm
Isoform 5: Cytoplasm
Cell Projection
Filopodium
Growth Cone
Dendrite
Cell Membrane
Sarcolemma
Cytoplasm
Not Secreted
Localizes To The Lateral Membrane And Intercalated Disks Of Myocytes
Alternative Protein Names Fibroblast Growth Factor 13 protein
Fgf-13 protein
Fibroblast Growth Factor Homologous Factor 2 protein
Fhf-2 protein
FGF13 protein
FHF2 protein

Information sourced from Uniprot.org

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