| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 5.4pg/mL |
| Detection Limit: | 15.6-1000pg/mL |
| Short Description : | This FGF13 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | FGF13 |
| Gene ID: | 2258 |
| Uniprot ID: | FGF13_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | Ubiquitously expressed. Predominantly expressed in the nervous system. |
| Post Translational Modifications | May be phosphorylated. |
| Function | Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons. |
| Protein Name | Fibroblast Growth Factor 13 Fgf-13 Fibroblast Growth Factor Homologous Factor 2 Fhf-2 |
| Database Links | Reactome: R-HSA-5576892 |
| Cellular Localisation | Isoform 1: Nucleus Isoform 2: Cytoplasm Nucleus Isoform 3: Cytoplasm Isoform 4: Cytoplasm Isoform 5: Cytoplasm Cell Projection Filopodium Growth Cone Dendrite Cell Membrane Sarcolemma Cytoplasm Not Secreted Localizes To The Lateral Membrane And Intercalated Disks Of Myocytes |
| Alternative ELISA Names | Fibroblast Growth Factor 13 ELISA kit Fgf-13 ELISA kit Fibroblast Growth Factor Homologous Factor 2 ELISA kit Fhf-2 ELISA kit FGF13 ELISA kit FHF2 ELISA kit |
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Information sourced from Uniprot.org