Human FGF-19 protein (Recombinant) (His-Tag) (STJP019447)

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STJP019447
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Host: HEK293 Cells
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FGF-19-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications.
Formulation: Liquid In 20mM Tris-HCl (pH8.0) containing 0.1M NaCl, 20% Glycerol
Concentration: 0.5 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
Gene Symbol: FGF19
Gene ID: 9965
Uniprot ID: FGF19_HUMAN
Immunogen Region: 23-216aa
Accession Number: NP_005108.1
Immunogen: Human
Immunogen Sequence: RPLAF SDAGPHVHYG WGDPIRLRHL YTSGPHGLSS CFLRIRADGV VDCARGQSAH SLLEIKAVAL RTVAIKGVHS VRYLCMGADG KMQGLLQYSE EDCAFEEEIR PDGYNVYRSE KHRLPVSLSS AKQRQLYKNR GFLPLSHFLP MLPMVPEEPE DLRGHLESDM FSSPLETDSM DPFGLVTGLE AVRSPSFEK
Tissue Specificity Expressed in fetal brain, cartilage, retina, and adult gall bladder.
Function Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
Protein Name Fibroblast Growth Factor 19
Fgf-19
Database Links Reactome: R-HSA-109704
Reactome: R-HSA-1257604
Reactome: R-HSA-1307965
Reactome: R-HSA-190322
Reactome: R-HSA-2219530
Reactome: R-HSA-5654228
Reactome: R-HSA-5654712
Reactome: R-HSA-5654719
Reactome: R-HSA-5654720
Reactome: R-HSA-5654733
Reactome: R-HSA-5673001
Reactome: R-HSA-6811558
Cellular Localisation Secreted
Alternative Protein Names Fibroblast Growth Factor 19 protein
Fgf-19 protein
FGF19 protein
UNQ334 protein
PRO533 protein

Information sourced from Uniprot.org