Human FcRn protein (Active Recombinant) (C-His (FCGRT) &No tag (B2M)) (STJP001116)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human FcRn Protein is produced by HEK293 cells expression system. The target heterodimer proteins are co-expressed with the sequence (Ala24-Ser297) of human FCGRT (Accession #NP_004098.1) fused with a 6×His tag at the C-terminus and the s
General Information
| Short Description | Active Recombinant-Human FcRn-C-His (FCGRT) &No tag (B2M) protein was developed in hek293 cells using the region Ile21-Met119. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | 1.Measured by its binding ability in a functional ELISA. Immobilized Human FCGRT&B2M at 5 Mu g/mL (100 Mu L/well) can bind biotinylated human IgG1 with a linear range of 1-6 Mu g/mL.|2.Immobilized Trastuzumab on COOH Chip can bind Human FCGRT&B2M Het |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Recombinant Human FcRn Protein is produced by HEK293 cells expression system. The target heterodimer proteins are co-expressed with the sequence (Ala24-Ser297) of human FCGRT (Accession #NP_004098.1) fused with a 6×His tag at the C-terminus and the s |
| Immunogen Region | Ile21-Met119 |
| Immunogen Sequence | AESHLSLLYHLTAVSSPAPG TPAFWVSGWLGPQQYLSYNS LRGEAEPCGAWVWENQVSWY WEKETTDLRIKEKLFLEAFK ALGGKGPYTLQGLLGCELGP DNTSVPTAKFALNGEEFMNF DLKQGTWGGDWPEALAISQR WQQQDKAANKELTFLLFSCP HRLREHLERGRGNLEWKEPP SMRLKARPSSPGFSVLTCSA FSFYPPELQLRFLRNGLAAG TGQGDFGPNSDGSFHASSS |
Additional Info
| Background | Active Recombinant Human FcRn Protein is produced by HEK293 cells expression system. The target heterodimer proteins are co-expressed with the sequence (Ala24-Ser297) of human FCGRT (Accession #NP_004098.1) fused with a 6×His tag at the C-terminus and the sequence (Ile21-Met119) of human B2M (Accession #NP_004039.1). |
Information sourced from Uniprot.org