Name: Human FCRL2/FCRH2/IRTA4 protein (Recombinant) (C-6His) (STJP020099)
SKU: STJP020099
Availability: InStock

Human FCRL2/FCRH2/IRTA4 protein (Recombinant) (C-6His) (STJP020099)

SKU:

STJP020099

£136.50 - £282.50

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation:	Unconjugated
Formulation:	Lyophilised from a 0.2 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 0.1 EU/Mu g of the protein by LAL method.

Gene Symbol:	FCRL2
Gene ID:	79368
Uniprot ID:	FCRL2_HUMAN
Immunogen Region:	Leu20-Asp395
Immunogen:	Recombinant Human FCRL2/FCRH2/IRTA4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu20-Asp395) of Human FCRL2/FCRH2/IRTA4 (Accession #NP_110391.2) fused with His at the C-terminus.
Immunogen Sequence:	LTLVAPSSVFEGDSIVLKCQ GEQNWKIQKMAYHKDNKELS VFKKFSDFLIQSAVLSDSGN YFCSTKGQLFLWDKTSNIVK IKVQELFQRPVLTASSFQPI EGGPVSLKCETRLSPQRLDV QLQFCFFRENQVLGSGWSSS PELQISAVWSEDTGSYWCKA ETVTHRIRKQSLQSQIHVQR IPISNVSLEIRAPGGQVTEG QKLILLCSVAGGTGNVTFSW YREATGTSMGKKTQRSLSA

Tissue Specificity	Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B-cell lines. Preferentially expressed in memory B-cells (at protein level).
Post Translational Modifications	Isoform 2 is N- and O-glycosylated, and phosphorylated.
Function	May have an regulatory role in normal and neoplastic B cell development.
Protein Name	Fc Receptor-Like Protein 2 Fcr-Like Protein 2 Fcrl2 Fc Receptor Homolog 2 Fcrh2 Ifgp Family Protein 4 Immunoglobulin Receptor Translocation-Associated Protein 4 Sh2 Domain-Containing Phosphatase Anchor Protein 1 Cd Antigen Cd307b
Database Links
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Fc Receptor-Like Protein 2 protein Fcr-Like Protein 2 protein Fcrl2 protein Fc Receptor Homolog 2 protein Fcrh2 protein Ifgp Family Protein 4 protein Immunoglobulin Receptor Translocation-Associated Protein 4 protein Sh2 Domain-Containing Phosphatase Anchor Protein 1 protein Cd Antigen Cd307b protein FCRL2 protein FCRH2 protein IFGP4 protein IRTA4 protein SPAP1 protein UNQ9236 protein PRO31998 protein

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJA0020368	Anti-CD307b/FCRL2/IRTA4 antibody [SAA1940] (STJA0020368)	Mouse	Monoclonal	Human	ELISA
STJP001898	Human HMGB2 protein (Recombinant) (C-6His) (STJP001898)	HEK293 cells
STJP001910	human SECTM1 protein (Recombinant) (C-6His) (STJP001910)	HEK293 cells
STJP002896	Human APP protein (Recombinant) (C-6His) (STJP002896)	HEK293 cells
STJP020058	Human LGR5/GPR49 protein protein (Recombinant) (C-6His) (STJP020058)	HEK293 cells

Human FCRL2/FCRH2/IRTA4 protein (Recombinant) (C-6His) (STJP020099)

General Information