Tissue Specificity | Specifically expressed in cardiac and skeletal muscle. |
Post Translational Modifications | |
Function | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. |
Protein Name | F-Box Only Protein 32Atrogin-1Muscle Atrophy F-Box ProteinMafbx |
Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-9615017Reactome: R-HSA-983168 |
Cellular Localisation | CytoplasmNucleusShuttles Between Cytoplasm And The Nucleus |
Alternative ELISA Names | F-Box Only Protein 32 ELISA kitAtrogin-1 ELISA kitMuscle Atrophy F-Box Protein ELISA kitMafbx ELISA kitFBXO32 ELISA kit |
output | |
Information sourced from Uniprot.org