Human FBP1 protein (Recombinant) (N-His) (STJP003900)

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STJP003900
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FBP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FBP1
Gene ID: 2203
Uniprot ID: F16P1_HUMAN
Immunogen Region: Met1-Gln338
Immunogen: Homo sapiens (Human)
Function Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity.increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Protein Name Fructose-1 -6-Bisphosphatase 1
Fbpase 1
D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 1
Liver Fbpase
Database Links Reactome: R-HSA-70263
Alternative Protein Names Fructose-1 -6-Bisphosphatase 1 protein
Fbpase 1 protein
D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 1 protein
Liver Fbpase protein
FBP1 protein
FBP protein

Information sourced from Uniprot.org

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