Human FBLIM1 (Filamin Binding LIM Protein 1) Sandwich ELISA Kit Kit (STJE0008807)

Human FBLIM1 (Filamin Binding LIM Protein 1) Sandwich ELISA Kit Kit (STJE0008807)

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STJE0008807
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.062ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This FBLIM1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: FBLIM1
Gene ID: 54751
Uniprot ID: FBLI1_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Isoform 1 and isoform 3 are expressed in heart, kidney, lung, pancreas, placenta and platelets. Isoform 2 is expressed in brain, heart, kidney, lung, pancreas, placenta, skeletal muscle and platelets.
Post Translational Modifications
Function Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
Protein Name Filamin-Binding Lim Protein 1
Fblp-1
Migfilin
Mitogen-Inducible 2-Interacting Protein
Mig2-Interacting Protein
Database Links Reactome: R-HSA-446353
Cellular Localisation Cell Junction
Focal Adhesion
Cytoplasm
Cytoskeleton
Stress Fiber
Associated With Actin Stress Fiber At Cell-Ecm Focal Adhesion Sites
Isoform 1 And Isoform 3 Are Recruited And Localized At Actin Stress Fibers And Clustered At Cell-Emc Adhesion Sites Through Interaction With Fermt2
Isoform 2 Is Localized At Actin Stress Fibers
Alternative ELISA Names Filamin-Binding Lim Protein 1 ELISA kit
Fblp-1 ELISA kit
Migfilin ELISA kit
Mitogen-Inducible 2-Interacting Protein ELISA kit
Mig2-Interacting Protein ELISA kit
FBLIM1 ELISA kit
FBLP1 ELISA kit
output

Information sourced from Uniprot.org

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