Name: Human EYA2 protein (Recombinant) (N-His) (STJP016381)
SKU: STJP016381
Availability: InStock

Human EYA2 protein (Recombinant) (N-His) (STJP016381)

SKU:

STJP016381

£208.50 - £1,163.50

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Short Description :	Recombinant-Human EYA2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:	Please contact us for further information.

Function	Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2.in this it is functionally redundant with EYA1.
Protein Name	Protein Phosphatase Eya2 Eyes Absent Homolog 2
Database Links	Reactome: R-HSA-5693565
Cellular Localisation	Cytoplasm Nucleus Retained In The Cytoplasm Via Interaction With Gnaz And Gnai2 Interaction With Six1 Six2 Six4 Or Six5 Is Required For Translocation To The Nucleus
Alternative Protein Names	Protein Phosphatase Eya2 protein Eyes Absent Homolog 2 protein EYA2 protein EAB1 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP017601	Human EYA2 protein (Recombinant) (His-Tag) (STJP017601)	E.coli	SDS-PAGE
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP015118	Human TAS1R1 protein protein (Recombinant) (N-His) (STJP015118)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP005538	Human ANO6 protein (Recombinant) (N-His) (STJP005538)	E.coli	ELISA/Immunogen/SDS-PAGE/WB

Human EYA2 protein (Recombinant) (N-His) (STJP016381)

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